About the Role The Senior Director, External Manufacturing Procurement, leads AstraZeneca’s procurement strategy and execution for outsourced contract manufacturing organizations (CMOs). This role is accountable for performance across multiple sites and countries, driving commercial excellence, robust governance, and reliable supply while meeting Safety, Health & Environment standards and all applicable regulations. The leader will manage and develop a team of Procurement professionals, build executive-level supplier relationships, and serve as a trusted partner to senior stakeholders across Operations and R&D. Key Accountabilities Strategic Leadership: Define the Procurement strategy for External Manufacturing and contribute expert input to broader Procurement strategy development. Delivery Management: Ensure objectives are met across all sites within remit, with disciplined value tracking and measurable financial and operational outcomes. Resource Planning: Partner with Line Managers to identify resource needs; secure and allocate resources to ensure timely delivery and progression of priorities. Team Leadership: Manage, motivate, coach, and set goals for Procurement leads; build a culture of leadership, creativity, collaboration, and high performance. Supplier Strategy & Negotiation: Lead negotiations and selection of outsourced service and equipment suppliers; oversee commercial governance and executive supplier relationships. Risk & Contingency Planning: Develop and manage contingency risk plans to assure on-site availability, quality, and budget adherence; escalate issues to protect patients and business reputation. Stakeholder Engagement: Lead key interactions with internal stakeholders to build reputation and broker cross-functional decisions and trade-offs. Best Practice & Compliance: Drive knowledge sharing and dissemination of best practices; establish and oversee processes ensuring compliance with Safety, Health & Environment standards, AstraZeneca policies, and applicable laws. Talent Development: Support senior staff in coaching and developing talent to maintain a healthy pipeline and succession for senior Procurement roles. People Leadership Span of Leadership: Approximately 10-15 total direct and indirect reports Global Remit A global role, working across EU, Asia and US Required Qualifications, Skills, and Experience External Manufacturing Expertise: Extensive leadership experience within external manufacturing and CMO environments. 10-15 years of industry experience with Supply Chain or Manufacturing Category Strategy & Value Delivery: Proven track record in setting category strategies and delivering multi-year improvement plans with measurable financial and operational outcomes. Performance Management: Demonstrated success holding teams and suppliers to account; establishing milestones; addressing underperformance promptly; ensuring delivery. Executive Communication: Exceptional communication and gravitas; trusted partner to senior leaders across Operations and R&D; adept at brokering cross-functional decisions and trade-offs. Commercial Governance: Demonstrated success leading executive supplier relationships, negotiating large and complex agreements, and driving commercial governance. Change Leadership: Strong record leading complex change programs with high adoption; experience deploying governance models and business process frameworks. Financial Acumen: Strong cost modelling, benchmarking, and P&L impact understanding; disciplined approach to value tracking. Core Requirements: Degree-level qualification; significant management experience in Procurement; excellent people management and motivational skills; ability to lead cross-functional teams; proven priority-setting and resource management in global/regional environments; excellent written and verbal communication; negotiation, collaboration, and interpersonal leadership skills; budgetary and resource planning experience; willingness to travel; strong conceptual, analytical, and strategic thinking; ability to influence strategically and persuade tactfully while maintaining positive relationships. Key Relationships Internal: Senior Procurement staff; leaders across Operations, R&D, and other functions. External: Global Suppliers and outsourced service providers; executive-level supplier stakeholders. Why AstraZeneca Join a company driven by science and innovation, dedicated to improving patient outcomes worldwide. You will shape external manufacturing strategies, lead high-impact teams, and forge strategic supplier partnerships that enable reliable, efficient, and compliant supply. Date Posted 16-Dec-2025 Closing Date 30-Dec-2025 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.