Principal Enterprise Architect Introduction to role: Are you ready to inspire change and make a significant impact? At AstraZeneca, we are committed to delivering life-changing medicines while embedding sustainability into every aspect of our work. As a Principal Enterprise Architect in Sustainability, you will play a pivotal role in ensuring our architecture decisions align with both business ambitions and IT strategy. This position is focused on strategic planning over a 1-5 year horizon, as well as immediate solution design projects. You will be instrumental in developing architecture standards, technology strategies, and roadmaps that support our mission to tackle the biggest sustainability challenges of our time. Accountabilities: As a Principal Enterprise Architect, you will: - Provide enterprise design thinking and support across various domains of architecture including Business, Application, Integration, Cloud, Data & Analytics, and AI/ML. - Lead efforts to ensure architecture decisions support business and IT strategy, ensuring compliance with AZ standards, blueprints, and roadmaps. - Participate in architecture assessments and reviews, contributing as a lead reviewing architect or domain expert. - Document and share knowledge and standard methodologies to develop the architecture capability and practice. - Be accountable for developing architecture standards, technology domain strategies, roadmaps, and blueprints. - Define and update 'Transition' and 'To-Be' architectures applying AZ guiding principles. - Support solution development efforts from portfolios, participate in IT initiatives, and provide guidance for better planning and decision-making. - Maintain a view of current and future state architecture within defined focus areas. - Develop architecture building blocks to support enterprise architecture implementation. - Lead or actively participate in enterprise domain teams and working groups. Essential Skills/Experience: - Relevant technical degree or equivalent - Experience as an enterprise architect authoring and completing architecture roadmaps - Experience producing application strategies/roadmaps for a global enterprise - Experience with rationalisation, consolidation, and integration of technology across business domains - Experience with large justification phase work – product evaluation, case formulation - Experience developing and influencing business strategies with multi-functional team impact - Experience developing and leading innovative solutions - Proven experience of leading change and challenging approaches/ideas - Experience developing and managing relationships with third-party suppliers - Experience designing complex technology solutions aligned to enterprise roadmaps - Experience in designing AI/ML solutions - Strong networking skills with good internal/external links - Strong communication, facilitation, and relationship-building skills - Ability to interpret and communicate technical information into business language - Awareness of marketplace developments and their relevance to AZ - Ability to work well in diverse, multinational teams and influence others positively - Open mind to learning new skills and capabilities - Ability to follow agile and incremental architecture approaches - Strong analytical skills on architecture trade-offs Desirable Skills/Experience: - Demonstrate initiative, strong customer orientation, and cross-cultural working - People development experience - Budget management experience - Masters or equivalent experience and/or professional certification - Experience in sustainability initiatives in large organizations - Good understanding of industry technology trends regarding Agentic AI - Good eye for business - Understanding of the pharmaceutical/healthcare industry When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca offers an environment where technical skills meet emotional intelligence. Join a team of highly qualified professionals who are persuasive communicators with empathy. We focus on the human impact of changes we drive, leading to complete solutions for the business. With the freedom to explore innovative technologies, there's never a dull moment as you create a significant footprint through continuous learning and growth. Ready to take on this exciting challenge? Apply now to join AstraZeneca's journey towards sustainability and innovation! Date Posted 04-Nov-2025 Closing Date 04-Dec-2025 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.