Job Description Position Summary: The role of Commercial Business Operations Senior Manager is responsible for partnering with the Business and Commercial Operations colleagues to ensure the execution of the commercial excellence activities within International Markets. This role will act as an internal subject matter expert of sales force effectiveness, commercial field metrics, data analysis, CRM operations and incentives compensation processes. The role requires substantial cross-functional collaboration with Compliance, Sales, Finance, Legal, and HR departments. Key responsibilities Incentives compensation: Responsible for all IC Communications, including plan documents, presentations, goal setting and payout communications, and regular reports for field force and leadership. Lead the execution of our plans with a very high degree of accuracy including the correct and timely calculation of payouts, effective documentation, and governance of our plans. Conduct ad hoc analyses to support incentive compensation plans. Data Stewarding: Develop and execute the organization's commercial data stewardship strategy to ensure data quality, accessibility, and governance in line with business objectives. Establish and enforce policies and procedures to maintain effective data stewardship. Implement and enforce Intl HEME data stewardship standards to maintain data accuracy and completeness Field Effectiveness: Support the diagnosis, identification and improvement the effectiveness of Commercial Field Teams Provides analytical expertise to support SFE activities Measures & improves commercial field teams motivation & engagement through the execution of the incentives compensation plan EDUCATION: Bachelor's degree in business finance, communications, marketing, or related discipline with relevant related experience - required SKILLS & EXPEREINCE: Minimum Requirements: Extensive sales/marketing commercial operations experience in a dynamic, international environment Excellent communication, interpersonal, and analytical skills Excellent stakeholder management skills Extensive direct experience with pharmaceutical data sourcing, integration, analysis, and reporting Ability and desire to understand the product needs of the future and influence all stakeholders to prioritize them Strong understanding of Web & Mobile CRM platforms (Veeva), ideally also IC planning platforms Preferred Qualifications: Attention to detail and committed follow-through in communications to stakeholders Pro-actively identifies issues and solves them Ability to work in a fast-paced, evolving environment; focus on multi-tasking and self-prioritized workload Strong focus on process delivery and execution Scientific aptitude and working knowledge of specialty or rare disease therapies area (preferable) Travel Position is based in London Paddington and travel of 20-30% may be required for country visits and training sessions. #LI-SG1 #LI-Hybrid Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.