POSTDOCTORAL RESEARCHER - H/F - Inserm

Main mission:

The successful candidate will work on an ANR-funded project aimed at studying the role of macrophages in cardiac fibrosis using single-cell and spatial transcriptomics methods.

Main activities:

• Animal models of cardiovascular diseases (surgery)
• Management of transgenic mouse lines
• Conducting and analysing single-cell and spatial transcriptomics experiments
• Presenting results at international conferences
• Preparing figures for scientific publications
• Writing scientific publications (in English)

Specific features and environment of the position:

Emerging Inserm CPJ team within the Paris Centre for Cardiovascular Research-Inserm U970, team of approximately 5 to 8 people.
International team, English is the working language for both spoken and written communication.

Knowledge:

• Cell biology
• Molecular biology
• Bioinformatics
• Cardiac pathophysiology
• Immunology, macrophage study models
• Cardio-immunology
• Fluent spoken/written scientific English

Hard Skills:

• Extensive experience in animal experimentation
• Extensive experience in animal surgery for cardiovascular pathology models
• Extensive experience in managing transgenic mouse lines
• Experience in preparing samples and single-cell RNA-seq libraries
• Extensive experience in single-cell RNA-seq analysis and spatial transcriptomics: analysis of multi-omics single-cell RNA-seq data and spatial transcriptomics with R or Python bioinformatics
• packages, data integration, data mining, etc.
• Extensive experience in flow cytometry

Soft Skills:

• Scientific rigour and organisation
• Autonomy
• Ability to work in a team

Desired experience:

2 to 4 years post-doctorate

Level of qualification and training

Bac +8